Partnering with communities for impact

OurDNA is a flagship project of the Centre for Population Genomics. The Centre is set up to:

• Include under-represented communities in genomic research;
• Explore the function and health relevance of human genes; and
• Improve the diagnosis and treatment of genetic diseases. 

The Centre is a not-for-profit joint initiative from two of Australia’s leading research institutes: the Garvan Institute of Medical Research in Sydney and the Murdoch Children’s Research Institute in Melbourne.

OurDNA is funded by: 

• The Centre for Population Genomics’ founding institutions: Garvan Institute of Medical Research and Murdoch Children’s Research Institute
• People who donate funds to our research
• Funding for this research has also been provided by the Australian Government’s Medical Research Future Fund (MRFF) grant 2015969 (CIA Daniel MacArthur; 2022-2027) from the Genomics Health Futures Mission and by the National Health and Medical Research Council (NHMRC) investigator grant 2009982 (CIA Daniel MacArthur; 2022-2026). The contents of this published material are solely the responsibility of the authors and do not reflect the views of the Commonwealth of Australia or the NHMRC.
• The OurDNA program also receives support from Google’s Digital Future Initiative. Read more about this collaboration here.

Yes, the OurDNA project has been approved by the certified Human Research Ethics Committee (HREC) of the Royal Children’s Hospital. The reference for our ethics approval is: HREC/91986/RCHM-2023

If you have any questions about the OurDNA ethics approval process, or wish to speak to someone independent of the research team, you may contact the Director of Research Operations at The Royal Children’s Hospital. You can phone the Director on (03) 9345 5044 or email them at rch.ethics@rch.org.au

OurDNA is currently funded until the end of 2027. It is our intention to continue our work until all Australian communities are represented and for the OurDNA database and sample bank to be available for as long as possible for researchers. 

To take part in OurDNA, you must:

• Be over 18 years old
• Be eligible for Medicare
• Be able to give a blood sample in Victoria or New South Wales
• Self-identify as having ancestry from one of the communities underrepresented in genetics resources. Visit this page to check which communities we are actively working with.
• People cannot participate if they or anyone in their close family has a known severe genetic health condition, like cystic fibrosis or muscular dystrophy. This does not include common conditions like inflammatory bowel disease, cancer or diabetes.

At the moment, Australians from the following ancestry groups are under represented or entirely missing in genetic resources:

• East African (e.g., Ethiopian, Ghanaian, Kenyan, Mauritian, Somali, South Sudanese, and Sudanese)
• North African and Middle Eastern (e.g., Assyrian, Chaldean, Egyptian, Iranian, Iraqi, Lebanese, Palestinian, Syrian and Turkish)
• Oceanian (e.g., Fijian, Mãori, Papua New Guinean, Samoan, and Tongan)
• South-East Asian (e.g., Cambodian, Filipino, Indonesian, Malay, Thai, and Vietnamese)

Australian doctors have also told us that it is hard to find information about these ancestry groups in the resources and databases they use to diagnose genetic and health conditions. 

OurDNA is working to engage with the communities underrepresented in genetic resources. Visit this page to check which communities we are actively working with.

While we are not working directly in Indigenous communities, we are an active member of the ALIGN and CONNECT consortia, national Indigenous-led efforts that are working to empower Aboriginal and Torres Strait Islander people in genomic medicine and research.

We provide technical advice for the development of genomic data infrastructure for nationally consistent, culturally appropriate, ethical storage, management, and sharing of genomic data to benefit Indigenous Australians.